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Identification of Kinase Inhibitors that Target Transcription Initiation by RNA Polymerase II

Our current understanding of eukaryotic transcription has greatly benefited from use of small molecule inhibitors that have delineated multiple regulatory steps in site-specific initiation and elongation of RNA synthesis by multiple forms of RNA polymerase (RNAP). This class of “transcription” drugs...

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Detalles Bibliográficos
Autores principales: Morachis, José M., Huang, Ruo, Emerson, Beverly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248145/
https://www.ncbi.nlm.nih.gov/pubmed/21378408