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Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells

Aging is one of the major risk factors of cancer. The onset of cancer can be postponed by pharmacological and dietary anti-aging interventions. We recently found in yeast cellular models of aging that lithocholic acid (LCA) extends longevity. Here we show that, at concentrations that are not cytotox...

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Detalles Bibliográficos
Autores principales: Goldberg, Alexander A., Beach, Adam, Davies, Gerald F., Harkness, Troy A. A., LeBlanc, Andréa, Titorenko, Vladimir I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248158/
https://www.ncbi.nlm.nih.gov/pubmed/21992775