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Wnt and Kras signaling-dark siblings in lung cancer

Aberrant Kras signaling is observed in a high percentage of human lung cancers while activating mutations in the Wnt/β-catenin signaling pathway are only rarely found. Our recent work has shown that the combined activation of both Kras and Wnt/β-catenin signaling leads to a dramatic increase in both...

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Detalles Bibliográficos
Autores principales: Pacheco-Pinedo, Eugenia C., Morrisey, Edward E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248175/
https://www.ncbi.nlm.nih.gov/pubmed/21753228