Cargando…
Wnt and Kras signaling-dark siblings in lung cancer
Aberrant Kras signaling is observed in a high percentage of human lung cancers while activating mutations in the Wnt/β-catenin signaling pathway are only rarely found. Our recent work has shown that the combined activation of both Kras and Wnt/β-catenin signaling leads to a dramatic increase in both...
Autores principales: | Pacheco-Pinedo, Eugenia C., Morrisey, Edward E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248175/ https://www.ncbi.nlm.nih.gov/pubmed/21753228 |
Ejemplares similares
-
Sotorasib in KRAS(G12C) mutated lung cancer: Can we rule out cracking KRAS led to worse overall survival?
por: Olivier, Timothée, et al.
Publicado: (2022) -
Hedgehog and WNT Signaling Hubs in Tracheal Morphogenesis
por: Frank, David B., et al.
Publicado: (2019) -
Immune modulatory effects of oncogenic KRAS in cancer
por: Hamarsheh, Shaima’a, et al.
Publicado: (2020) -
A Nexus between Genetic and Non-Genetic Mechanisms Guides KRAS Inhibitor Resistance in Lung Cancer
por: Kulkarni, Prakash, et al.
Publicado: (2023) -
Metformin: A New Inhibitor of the Wnt Signaling Pathway in Cancer
por: Conza, Domenico, et al.
Publicado: (2023)