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YB-1 drives preneoplastic progression: Insight into opportunities for cancer prevention

Surprisingly little is known about the underlying genetic events that trigger the progression of a normal cell into a cancerous cell. We recently developed a YB-1-driven model of pre-malignancy where we uncovered that the oncogene promotes genomic instability through cell cycle checkpoint slippage a...

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Detalles Bibliográficos
Autores principales: Davies, Alastair H., Dunn, Sandra E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248184/
https://www.ncbi.nlm.nih.gov/pubmed/21576761