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No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

The Warburg effect describes the circumstance that tumor cells preferentially use glycolysis rather than oxidative phosphorylation for energy production. It has been reported that this metabolic reconfiguration originates from a switch in the expression of alternative splice forms (PKM1 and PKM2) of...

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Detalles Bibliográficos
Autores principales: Bluemlein, Katharina, Grüning, Nana-Maria, Feichtinger, René G., Lehrach, Hans, Kofler, Barbara, Ralser, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248187/
https://www.ncbi.nlm.nih.gov/pubmed/21789790