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Class III β-Tubulin Counteracts the Ability of Paclitaxel to Inhibit Cell Migration

Class III β-tubulin (β3) is associated with tumor aggressiveness, resistance to therapy, and patient relapse. To elucidate its action, we tested β3's effect on cell migration. Expression of β3 in HeLa and MCF-7 did not alter the intrinsic rate of cell migration, but it prevented the inhibition...

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Detalles Bibliográficos
Autores principales: Ganguly, Anutosh, Yang, Hailing, Cabral, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248193/
https://www.ncbi.nlm.nih.gov/pubmed/21576762