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Elevated PI3K signaling drives multiple Breast Cancer subtypes

Most human breast tumors have mutations that elevate signaling through a key metabolic pathway that is induced by insulin and a number of growth factors. This pathway serves to activate an enzyme known as phosphatidylinositol 3' kinase (PI3K) as well as to regulate proteins that signal in respo...

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Detalles Bibliográficos
Autores principales: Adams, Jessica R., Schachter, Nathan F., Liu, Jeff C., Zacksenhaus, Eldad, Egan, Sean E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248195/
https://www.ncbi.nlm.nih.gov/pubmed/21646685