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Mouse Models to Interrogate the Implications of the Differentiation Status in the Ontogeny of Gliomas

Glioblastoma Multiforme (GBM) is the most common and lethal of human primary central nervous system (CNS) tumors, with a median survival of 14-16 months despite optimal surgery, radiation and chemotherapy. A reason for this dismal prognosis is insufficient understanding of the ontogeny of GBMs, whic...

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Detalles Bibliográficos
Autores principales: Muñoz, Diana Marcela, Guha, Abhijit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248213/
https://www.ncbi.nlm.nih.gov/pubmed/21896959