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Chronic myeloid leukemia stem cells in the era of targeted therapies: resistance, persistence and long-term dormancy

Targeted therapies of chronic myeloid leukemia (CML) using tyrosine kinase inhibitors (TKI) have profoundly changed the natural history of the disease with a major impact on survival. Molecular monitoring with BCR-ABL quantification shows that a status of undetectable molecular residual disease (UMR...

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Detalles Bibliográficos
Autores principales: Chomel, Jean-Claude, Turhan, Ali G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248215/
https://www.ncbi.nlm.nih.gov/pubmed/21946665