Improved Bevirimat resistance prediction by combination of structural and sequence-based classifiers

BACKGROUND: Maturation inhibitors such as Bevirimat are a new class of antiretroviral drugs that hamper the cleavage of HIV-1 proteins into their functional active forms. They bind to these preproteins and inhibit their cleavage by the HIV-1 protease, resulting in non-functional virus particles. Nev...

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Detalles Bibliográficos
Autores principales: Dybowski, J Nikolaj, Riemenschneider, Mona, Hauke, Sascha, Pyka, Martin, Verheyen, Jens, Hoffmann, Daniel, Heider, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248369/
https://www.ncbi.nlm.nih.gov/pubmed/22082002
http://dx.doi.org/10.1186/1756-0381-4-26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248369/
https://www.ncbi.nlm.nih.gov/pubmed/22082002
http://dx.doi.org/10.1186/1756-0381-4-26

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