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Prediction of Drug Combinations by Integrating Molecular and Pharmacological Data

Combinatorial therapy is a promising strategy for combating complex disorders due to improved efficacy and reduced side effects. However, screening new drug combinations exhaustively is impractical considering all possible combinations between drugs. Here, we present a novel computational approach t...

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Detalles Bibliográficos
Autores principales: Zhao, Xing-Ming, Iskar, Murat, Zeller, Georg, Kuhn, Michael, van Noort, Vera, Bork, Peer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248384/
https://www.ncbi.nlm.nih.gov/pubmed/22219721
http://dx.doi.org/10.1371/journal.pcbi.1002323