Cargando…
Prediction of Drug Combinations by Integrating Molecular and Pharmacological Data
Combinatorial therapy is a promising strategy for combating complex disorders due to improved efficacy and reduced side effects. However, screening new drug combinations exhaustively is impractical considering all possible combinations between drugs. Here, we present a novel computational approach t...
Autores principales: | Zhao, Xing-Ming, Iskar, Murat, Zeller, Georg, Kuhn, Michael, van Noort, Vera, Bork, Peer |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248384/ https://www.ncbi.nlm.nih.gov/pubmed/22219721 http://dx.doi.org/10.1371/journal.pcbi.1002323 |
Ejemplares similares
-
Network Neighbors of Drug Targets Contribute to Drug Side-Effect Similarity
por: Brouwers, Lucas, et al.
Publicado: (2011) -
Drug-Induced Regulation of Target Expression
por: Iskar, Murat, et al.
Publicado: (2010) -
Discovery and validation of the antimetastatic activity of citalopram in colorectal cancer
por: Iskar, Murat, et al.
Publicado: (2015) -
CART—a chemical annotation retrieval toolkit
por: Deghou, Samy, et al.
Publicado: (2016) -
Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding
por: Iskar, Murat, et al.
Publicado: (2013)