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Epigenetic Changes of CXCR4 and Its Ligand CXCL12 as Prognostic Factors for Sporadic Breast Cancer

Chemokines and their receptors are involved in the development and cancer progression. The chemokine CXCL12 interacts with its receptor, CXCR4, to promote cellular adhesion, survival, proliferation and migration. The CXCR4 gene is upregulated in several types of cancers, including skin, lung, pancre...

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Detalles Bibliográficos
Autores principales: Ramos, Edneia A. S., Grochoski, Mariana, Braun-Prado, Karin, Seniski, Gerusa G., Cavalli, Iglenir J., Ribeiro, Enilze M. S. F., Camargo, Anamaria A., Costa, Fabrício F., Klassen, Giseli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248418/
https://www.ncbi.nlm.nih.gov/pubmed/22220212
http://dx.doi.org/10.1371/journal.pone.0029461