Probing the SELEX Process with Next-Generation Sequencing

BACKGROUND: SELEX is an iterative process in which highly diverse synthetic nucleic acid libraries are selected over many rounds to finally identify aptamers with desired properties. However, little is understood as how binders are enriched during the selection course. Next-generation sequencing off...

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Detalles Bibliográficos
Autores principales: Schütze, Tatjana, Wilhelm, Barbara, Greiner, Nicole, Braun, Hannsjörg, Peter, Franziska, Mörl, Mario, Erdmann, Volker A., Lehrach, Hans, Konthur, Zoltán, Menger, Marcus, Arndt, Peter F., Glökler, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248438/
https://www.ncbi.nlm.nih.gov/pubmed/22242135
http://dx.doi.org/10.1371/journal.pone.0029604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248438/
https://www.ncbi.nlm.nih.gov/pubmed/22242135
http://dx.doi.org/10.1371/journal.pone.0029604

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