Efficient Maximum Likelihood Estimation of Kinetic Rate Constants from Macroscopic Currents

A new method is described that accurately estimates kinetic constants, conductance and number of ion channels from macroscopic currents. The method uses both the time course and the strength of correlations between different time points of macroscopic currents and utilizes the property of semisepara...

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Detalles Bibliográficos
Autores principales: Stepanyuk, Andrey R., Borisyuk, Anya L., Belan, Pavel V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248447/
https://www.ncbi.nlm.nih.gov/pubmed/22242142
http://dx.doi.org/10.1371/journal.pone.0029731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248447/
https://www.ncbi.nlm.nih.gov/pubmed/22242142
http://dx.doi.org/10.1371/journal.pone.0029731

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