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MAPK/ERK Signaling Regulates Insulin Sensitivity to Control Glucose Metabolism in Drosophila

The insulin/IGF-activated AKT signaling pathway plays a crucial role in regulating tissue growth and metabolism in multicellular animals. Although core components of the pathway are well defined, less is known about mechanisms that adjust the sensitivity of the pathway to extracellular stimuli. In h...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Thompson, Barry J., Hietakangas, Ville, Cohen, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248469/
https://www.ncbi.nlm.nih.gov/pubmed/22242005
http://dx.doi.org/10.1371/journal.pgen.1002429