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A Novel Human Cytomegalovirus Locus Modulates Cell Type-Specific Outcomes of Infection

Clinical strains of HCMV encode 20 putative ORFs within a region of the genome termed ULb′ that are postulated to encode functions related to persistence or immune evasion. We have previously identified ULb′-encoded pUL138 as necessary, but not sufficient, for HCMV latency in CD34(+) hematopoietic p...

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Detalles Bibliográficos
Autores principales: Umashankar, Mahadevaiah, Petrucelli, Alex, Cicchini, Louis, Caposio, Patrizia, Kreklywich, Craig N., Rak, Michael, Bughio, Farah, Goldman, Devorah C., Hamlin, Kimberly L., Nelson, Jay A., Fleming, William H., Streblow, Daniel N., Goodrum, Felicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248471/
https://www.ncbi.nlm.nih.gov/pubmed/22241980
http://dx.doi.org/10.1371/journal.ppat.1002444