Cargando…
A Genetic Screening Strategy Identifies Novel Regulators of the Proteostasis Network
A hallmark of diseases of protein conformation and aging is the appearance of protein aggregates associated with cellular toxicity. We posit that the functional properties of the proteostasis network (PN) protect the proteome from misfolding and combat the proteotoxic events leading to cellular path...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248563/ https://www.ncbi.nlm.nih.gov/pubmed/22242008 http://dx.doi.org/10.1371/journal.pgen.1002438 |