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Roles of Serotonergic and Adrenergic Receptors in the Antinociception of Selective Cyclooxygenase-2 Inhibitor in the Rat Spinal Cord

BACKGROUND: The analgesic mechanisms of cyclooxygenase (COX)-2 inhibitors have been explained mainly on the basis of the inhibition of prostaglandin biosynthesis. However, several lines of evidence suggest that their analgesic effects are mediated through serotonergic or adrenergic transmissions. We...

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Detalles Bibliográficos
Autores principales: Jeong, Hye Jin, Lee, Seong Heon, Cho, Soo Young, Lee, Cha Sup, Jeong, Cheol Won, Yoon, Myung Ha, Kim, Woong Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248580/
https://www.ncbi.nlm.nih.gov/pubmed/22220238
http://dx.doi.org/10.3344/kjp.2011.24.4.179