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Influenza emergence in the face of evolutionary constraints
Different influenza subtypes can evolve at very different rates, but the causes are not well understood. In this paper, we explore whether differences in transmissibility between subtypes can play a role if there are fitness constraints on antigenic evolution. We investigate the problem using a math...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248728/ https://www.ncbi.nlm.nih.gov/pubmed/21775331 http://dx.doi.org/10.1098/rspb.2011.1168 |