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Benefits, challenges and obstacles of adaptive clinical trial designs
In recent years, the use of adaptive design methods in pharmaceutical/clinical research and development has become popular due to its flexibility and efficiency for identifying potential signals of clinical benefit of the test treatment under investigation. The flexibility and efficiency, however, i...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248853/ https://www.ncbi.nlm.nih.gov/pubmed/22129361 http://dx.doi.org/10.1186/1750-1172-6-79 |