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Benefits, challenges and obstacles of adaptive clinical trial designs

In recent years, the use of adaptive design methods in pharmaceutical/clinical research and development has become popular due to its flexibility and efficiency for identifying potential signals of clinical benefit of the test treatment under investigation. The flexibility and efficiency, however, i...

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Detalles Bibliográficos
Autores principales: Chow, Shein-Chung, Corey, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248853/
https://www.ncbi.nlm.nih.gov/pubmed/22129361
http://dx.doi.org/10.1186/1750-1172-6-79