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The proliferation rate paradox in antimitotic chemotherapy
Cytotoxic cancer chemotherapy drugs are believed to gain selectivity by targeting cells that proliferate rapidly. However, the proliferation rate is low in many chemosensitive human cancers, and it is not clear how a drug that only kills dividing cells could promote tumor regression. Four potential...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The American Society for Cell Biology
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248889/ https://www.ncbi.nlm.nih.gov/pubmed/22210845 http://dx.doi.org/10.1091/mbc.E10-04-0335 |