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Rapid degradation of cyclooxygenase-1 and hematopoietic prostaglandin D synthase through ubiquitin–proteasome system in response to intracellular calcium level

Cyclooxygenase (COX)-1 and hematopoietic prostaglandin (PG) D synthase (H-PGDS) proteins, which are both involved in the arachidonate cascade, were stable in human megakaryocytic MEG-01 cells. In contrast, once the intracellular calcium level was increased by treatment with a calcium ionophore, both...

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Detalles Bibliográficos
Autores principales:	Yazaki, Misato, Kashiwagi, Kaori, Aritake, Kosuke, Urade, Yoshihiro, Fujimori, Ko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248891/ https://www.ncbi.nlm.nih.gov/pubmed/22049022 http://dx.doi.org/10.1091/mbc.E11-07-0623

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