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Connecdenn 3/DENND1C binds actin linking Rab35 activation to the actin cytoskeleton

The small GTPase Rab35 regulates endosomal membrane trafficking but also recruits effectors that modulate actin assembly and organization. Differentially expressed in normal and neoplastic cells (DENN)–domain proteins are a newly identified class of Rab guanine-nucleotide exchange factors (GEFs) tha...

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Detalles Bibliográficos
Autores principales: Marat, Andrea L., Ioannou, Maria S., McPherson, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248895/
https://www.ncbi.nlm.nih.gov/pubmed/22072793
http://dx.doi.org/10.1091/mbc.E11-05-0474