Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling

Sealing of phagosomes is accompanied by the disappearance of phosphatidylinositol (4,5)-bisphosphate (PtdIns(4,5)P(2)) from their cytoplasmic leaflet. Elimination of PtdIns(4,5)P(2), which is required for actin remodeling during phagosome formation, has been attributed to hydrolysis by phospholipase...

Descripción completa

Detalles Bibliográficos
Autores principales: Bohdanowicz, Michal, Balkin, Daniel M., De Camilli, Pietro, Grinstein, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248896/
https://www.ncbi.nlm.nih.gov/pubmed/22072788
http://dx.doi.org/10.1091/mbc.E11-06-0489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248896/
https://www.ncbi.nlm.nih.gov/pubmed/22072788
http://dx.doi.org/10.1091/mbc.E11-06-0489

Ejemplares similares