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RNA-related nuclear functions of human Pat1b, the P-body mRNA decay factor

The evolutionarily conserved Pat1 proteins are P-body components recently shown to play important roles in cytoplasmic gene expression control. Using human cell lines, we demonstrate that human Pat1b is a shuttling protein whose nuclear export is mediated via a consensus NES sequence and Crm1, as ev...

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Detalles Bibliográficos
Autores principales: Marnef, Aline, Weil, Dominique, Standart, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248899/
https://www.ncbi.nlm.nih.gov/pubmed/22090346
http://dx.doi.org/10.1091/mbc.E11-05-0415