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The kinase activity of human Rio1 is required for final steps of cytoplasmic maturation of 40S subunits

RIO proteins form a conserved family of atypical protein kinases. Humans possess three distinct RIO kinases—hRio1, hRio2, and hRio3, of which only hRio2 has been characterized with respect to its role in ribosomal biogenesis. Here we show that both hRio1 and hRio3, like hRio2, are associated with pr...

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Detalles Bibliográficos
Autores principales: Widmann, Barbara, Wandrey, Franziska, Badertscher, Lukas, Wyler, Emanuel, Pfannstiel, Jens, Zemp, Ivo, Kutay, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248900/
https://www.ncbi.nlm.nih.gov/pubmed/22072790
http://dx.doi.org/10.1091/mbc.E11-07-0639