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FAT10 is a proteasomal degradation signal that is itself regulated by ubiquitination

FAT10 is a ubiquitin-like protein modifier that is induced in vertebrates following certain inflammatory stimuli. Its functions and the repertoire of its target substrates have remained elusive. In contrast to ubiquitin, its cellular abundance is tightly controlled by both transcriptional and posttr...

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Detalles Bibliográficos
Autores principales: Buchsbaum, Samuel, Bercovich, Beatrice, Ciechanover, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248901/
https://www.ncbi.nlm.nih.gov/pubmed/22072791
http://dx.doi.org/10.1091/mbc.E11-07-0609