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UHRF1 phosphorylation by cyclin A2/cyclin-dependent kinase 2 is required for zebrafish embryogenesis

Ubiquitin-like, containing PHD and RING finger domains 1 (uhrf1) is regulated at the transcriptional level during the cell cycle and in developing zebrafish embryos. We identify phosphorylation as a novel means of regulating UHRF1 and demonstrate that Uhrf1 phosphorylation is required for gastrulati...

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Detalles Bibliográficos
Autores principales: Chu, Jaime, Loughlin, Elizabeth A., Gaur, Naseem A., SenBanerjee, Sucharita, Jacob, Vinitha, Monson, Christopher, Kent, Brandon, Oranu, Amanke, Ding, Yuanying, Ukomadu, Chinweike, Sadler, Kirsten C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248904/
https://www.ncbi.nlm.nih.gov/pubmed/22072796
http://dx.doi.org/10.1091/mbc.E11-06-0487