Cargando…

An association between type Iγ PI4P 5-kinase and Exo70 directs E-cadherin clustering and epithelial polarization

E-Cadherin–mediated formation of adherens junctions (AJs) is essential for the morphogenesis of epithelial cells. However, the mechanisms underlying E-cadherin clustering and AJ maturation are not fully understood. Here we report that type Iγ phosphatidylinositol-4-phosphate 5-kinase (PIPKIγ) associ...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiong, Xunhao, Xu, Qingwen, Huang, Yan, Singh, Raman Deep, Anderson, Richard, Leof, Edward, Hu, Jinghua, Ling, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248907/
https://www.ncbi.nlm.nih.gov/pubmed/22049025
http://dx.doi.org/10.1091/mbc.E11-05-0449