Probing Binding Pocket of Serotonin Transporter by Single Molecular Force Spectroscopy on Living Cells

The serotonin transporter (SERT) terminates neurotransmission by removing serotonin from the synaptic cleft. In addition, it is the site of action of antidepressants (which block the transporter) and of amphetamines (which induce substrate efflux). The interaction energies involved in binding of suc...

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Detalles Bibliográficos
Autores principales: Wildling, Linda, Rankl, Christian, Haselgrübler, Thomas, Gruber, Hermann J., Holy, Marion, Newman, Amy Hauck, Zou, Mu-Fa, Zhu, Rong, Freissmuth, Michael, Sitte, Harald H., Hinterdorfer, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249061/
https://www.ncbi.nlm.nih.gov/pubmed/22033932
http://dx.doi.org/10.1074/jbc.M111.304873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249061/
https://www.ncbi.nlm.nih.gov/pubmed/22033932
http://dx.doi.org/10.1074/jbc.M111.304873

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