Dual modification of Alzheimer’s disease PHF-tau protein by lysine methylation and ubiquitylation: a mass spectrometry approach

In sporadic Alzheimer’s disease (AD), neurofibrillary lesion formation is preceded by extensive post-translational modification of the microtubule associated protein tau. To identify the modification signature associated with tau lesion formation at single amino acid resolution, immunopurified paire...

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Detalles Bibliográficos
Autores principales: Thomas, Stefani N., Funk, Kristen E., Wan, Yunhu, Liao, Zhongping, Davies, Peter, Kuret, Jeff, Yang, Austin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249157/
https://www.ncbi.nlm.nih.gov/pubmed/22033876
http://dx.doi.org/10.1007/s00401-011-0893-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249157/
https://www.ncbi.nlm.nih.gov/pubmed/22033876
http://dx.doi.org/10.1007/s00401-011-0893-0

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