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A novel category of antigens enabling CTL immunity to tumor escape variants: Cinderella antigens
Deficiencies in MHC class I antigen presentation are a common feature of tumors and allows escape from cytotoxic T lymphocyte (CTL)-mediated killing. It is crucial to take this capacity of tumors into account for the development of T-cell-based immunotherapy, as it may strongly impair their effectiv...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249164/ https://www.ncbi.nlm.nih.gov/pubmed/22116347 http://dx.doi.org/10.1007/s00262-011-1160-x |