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A novel category of antigens enabling CTL immunity to tumor escape variants: Cinderella antigens

Deficiencies in MHC class I antigen presentation are a common feature of tumors and allows escape from cytotoxic T lymphocyte (CTL)-mediated killing. It is crucial to take this capacity of tumors into account for the development of T-cell-based immunotherapy, as it may strongly impair their effectiv...

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Detalles Bibliográficos
Autores principales: Seidel, Ursula J. E., Oliveira, Claudia C., Lampen, Margit H., van Hall, Thorbald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249164/
https://www.ncbi.nlm.nih.gov/pubmed/22116347
http://dx.doi.org/10.1007/s00262-011-1160-x