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Domain Architecture of a Calcium-Permeable AMPA Receptor in a Ligand-Free Conformation

Ligand-gated ion channels couple the free energy of agonist binding to the gating of selective transmembrane ion pores, permitting cells to regulate ion flux in response to external chemical stimuli. However, the stereochemical mechanisms responsible for this coupling remain obscure. In the case of...

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Detalles Bibliográficos
Autores principales: Midgett, Charles R., Gill, Avinash, Madden, Dean R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249379/
https://www.ncbi.nlm.nih.gov/pubmed/22232575
http://dx.doi.org/10.3389/fnmol.2011.00056