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Domain Architecture of a Calcium-Permeable AMPA Receptor in a Ligand-Free Conformation
Ligand-gated ion channels couple the free energy of agonist binding to the gating of selective transmembrane ion pores, permitting cells to regulate ion flux in response to external chemical stimuli. However, the stereochemical mechanisms responsible for this coupling remain obscure. In the case of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Research Foundation
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249379/ https://www.ncbi.nlm.nih.gov/pubmed/22232575 http://dx.doi.org/10.3389/fnmol.2011.00056 |