Structural models of CFTR–AMPK and CFTR–PKA interactions: R-domain flexibility is a key factor in CFTR regulation

Cystic fibrosis (CF), the most common lethal genetic disease among Caucasians, is caused by mutations in cystic fibrosis transmembrane conductance regulator (CFTR). CFTR’s main role is to transport chloride ions across epithelial cell membranes. It also regulates many cell functions. However, the ex...

Descripción completa

Detalles Bibliográficos
Autores principales: Siwiak, Marian, Edelman, Aleksander, Zielenkiewicz, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249538/
https://www.ncbi.nlm.nih.gov/pubmed/21455600
http://dx.doi.org/10.1007/s00894-011-1029-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249538/
https://www.ncbi.nlm.nih.gov/pubmed/21455600
http://dx.doi.org/10.1007/s00894-011-1029-0

Ejemplares similares