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Selective Changes of GABA(A) Channel Subunit mRNAs in the Hippocampus and Orbitofrontal Cortex but not in Prefrontal Cortex of Human Alcoholics

Alcohol dependence is a common chronic relapsing disorder. The development of alcohol dependence has been associated with changes in brain GABA(A) channel-mediated neurotransmission and plasticity. We have examined mRNA expression of the GABA(A) channel subunit genes in three brain regions in indivi...

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Detalles Bibliográficos
Autores principales: Jin, Zhe, Bazov, Igor, Kononenko, Olga, Korpi, Esa R., Bakalkin, Georgy, Birnir, Bryndis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249692/
https://www.ncbi.nlm.nih.gov/pubmed/22319468
http://dx.doi.org/10.3389/fncel.2011.00030