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High Performance Liquid Chromatographic Fluorescence Detection Method for the Quantification of Rivastigmine in Rat Plasma and Brain: Application to Preclinical Pharmacokinetic Studies in Rats

A highly sensitive and selective high performance liquid chromatographic fluorescence detection method has been developed and validated for the quantification of rivastigmine in rat plasma and brain. Protein precipitation and one-step liquid–liquid extraction techniques were utilized for the extract...

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Detalles Bibliográficos
Autores principales: Arumugam, K, Chamallamudi, MR, Mallayasamy, SR, Mullangi, R, Ganesan, S, Jamadar, L, Ranjithkumar, A, Udupa, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249745/
https://www.ncbi.nlm.nih.gov/pubmed/22224039
http://dx.doi.org/10.4103/0975-1483.90244