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Identification of the protease inhibitor miraziridine A in the Red sea sponge Theonella swinhoei
BACKGROUND: Miraziridine A, a natural peptide isolated from a marine sponge, is a potent cathepsin B inhibitor with a second-order rate constant of 1.5 × 10(4) M(-1) s(-1). In the present study, miraziridine A was isolated from the Red Sea sponge Theonella swinhoei on the basis of chromatographic an...
Autores principales: | Tabares, Paula, Degel, Björn, Schaschke, Norbert, Hentschel, Ute, Schirmeister, Tanja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250042/ https://www.ncbi.nlm.nih.gov/pubmed/22224064 http://dx.doi.org/10.4103/0974-8490.91047 |
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