TRAIL Gene-Armed Oncolytic Poxvirus and Oxaliplatin Can Work Synergistically against Colorectal Cancer

We have explored a unique combination therapy for metastatic colorectal cancer. This strategy combines a potent and new oncolytic poxvirus expressing a membrane-bound tumor necrosis factor-related apoptosis-inducing ligand (TRAIL or TNFSF10) and oxaliplatin (Ox) chemotherapy. We hypothesized that TR...

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Detalles Bibliográficos
Autores principales: Ziauddin, Mohammed F, Guo, Z. Sheng, O'Malley, Mark E., Austin, Frances, Popovic, Petar J., Kavanagh, Maihgan A., Li, Jun, Sathaiah, Magesh, Thirunavukkarasu, Prag, Fang, Bingliang, Lee, Yong J., Bartlett, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250063/
https://www.ncbi.nlm.nih.gov/pubmed/20182517
http://dx.doi.org/10.1038/gt.2010.5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250063/
https://www.ncbi.nlm.nih.gov/pubmed/20182517
http://dx.doi.org/10.1038/gt.2010.5

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