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Estimating the voltage-dependent free energy change of ion channels using the median voltage for activation
Voltage-gated ion channels are crucial for electrical activity and chemical signaling in a variety of cell types. Structure-activity studies involving electrophysiological characterization of mutants are widely used and allow us to quickly realize the energetic effects of a mutation by measuring mac...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250103/ https://www.ncbi.nlm.nih.gov/pubmed/22155736 http://dx.doi.org/10.1085/jgp.201110722 |