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A Modified Extraction Method of Circulating Free DNA for Epidermal Growth Factor Receptor Mutation Analysis

PURPOSE: Circulating free DNA (cfDNA) in plasma is promising to be a surrogate for tumor tissue DNA. However, not all epidermal growth factor receptor (EGFR) mutations in tumor tissue DNA has been detected in matched cfDNA, at least partly due to inefficient cfDNA extraction method. The purpose of t...

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Detalles Bibliográficos
Autores principales: Yuan, Haihua, Zhu, Zhong-Zheng, Lu, Yachao, Liu, Feng, Zhang, Wenying, Huang, Gang, Zhu, Guanshan, Jiang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250323/
https://www.ncbi.nlm.nih.gov/pubmed/22187243
http://dx.doi.org/10.3349/ymj.2012.53.1.132