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Quantile-Specific Penetrance of Genes Affecting Lipoproteins, Adiposity and Height
Quantile-dependent penetrance is proposed to occur when the phenotypic expression of a SNP depends upon the population percentile of the phenotype. To illustrate the phenomenon, quantiles of height, body mass index (BMI), and plasma lipids and lipoproteins were compared to genetic risk scores (GRS)...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250394/ https://www.ncbi.nlm.nih.gov/pubmed/22235250 http://dx.doi.org/10.1371/journal.pone.0028764 |