Pre-Existing Isoniazid Resistance, but Not the Genotype of Mycobacterium Tuberculosis Drives Rifampicin Resistance Codon Preference in Vitro

Both the probability of a mutation occurring and the ability of the mutant to persist will influence the distribution of mutants that arise in a population. We studied the interaction of these factors for the in vitro selection of rifampicin (RIF)-resistant mutants of Mycobacterium tuberculosis. We...

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Detalles Bibliográficos
Autores principales: Bergval, Indra, Kwok, Brian, Schuitema, Anja, Kremer, Kristin, van Soolingen, Dick, Klatser, Paul, Anthony, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250395/
https://www.ncbi.nlm.nih.gov/pubmed/22235262
http://dx.doi.org/10.1371/journal.pone.0029108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250395/
https://www.ncbi.nlm.nih.gov/pubmed/22235262
http://dx.doi.org/10.1371/journal.pone.0029108

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