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Denervation Causes Fiber Atrophy and Myosin Heavy Chain Co-Expression in Senescent Skeletal Muscle

Although denervation has long been implicated in aging muscle, the degree to which it is causes the fiber atrophy seen in aging muscle is unknown. To address this question, we quantified motoneuron soma counts in the lumbar spinal cord using choline acetyl transferase immunhistochemistry and quantif...

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Detalles Bibliográficos
Autores principales: Rowan, Sharon L., Rygiel, Karolina, Purves-Smith, Fennigje M., Solbak, Nathan M., Turnbull, Douglas M., Hepple, Russell T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250397/
https://www.ncbi.nlm.nih.gov/pubmed/22235261
http://dx.doi.org/10.1371/journal.pone.0029082