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Interferon and Biologic Signatures in Dermatomyositis Skin: Specificity and Heterogeneity across Diseases

BACKGROUND: Dermatomyositis (DM) is an autoimmune disease that mainly affects the skin, muscle, and lung. The pathogenesis of skin inflammation in DM is not well understood. METHODOLOGY AND FINDINGS: We analyzed genome-wide expression data in DM skin and compared them to those from healthy controls....

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Detalles Bibliográficos
Autores principales: Wong, David, Kea, Bory, Pesich, Rob, Higgs, Brandon W., Zhu, Wei, Brown, Patrick, Yao, Yihong, Fiorentino, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250414/
https://www.ncbi.nlm.nih.gov/pubmed/22235269
http://dx.doi.org/10.1371/journal.pone.0029161