Cargando…
Interferon and Biologic Signatures in Dermatomyositis Skin: Specificity and Heterogeneity across Diseases
BACKGROUND: Dermatomyositis (DM) is an autoimmune disease that mainly affects the skin, muscle, and lung. The pathogenesis of skin inflammation in DM is not well understood. METHODOLOGY AND FINDINGS: We analyzed genome-wide expression data in DM skin and compared them to those from healthy controls....
Autores principales: | Wong, David, Kea, Bory, Pesich, Rob, Higgs, Brandon W., Zhu, Wei, Brown, Patrick, Yao, Yihong, Fiorentino, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250414/ https://www.ncbi.nlm.nih.gov/pubmed/22235269 http://dx.doi.org/10.1371/journal.pone.0029161 |
Ejemplares similares
-
AB015. Skin disease activity and autoantibody phenotype are major determinants of blood interferon signatures in dermatomyositis
por: Tabata, Mika, et al.
Publicado: (2021) -
Suppression of soluble T cell-associated proteins by an anti-interferon-α monoclonal antibody in adult patients with dermatomyositis or polymyositis
por: Guo, Xiang, et al.
Publicado: (2014) -
A phase 1b clinical trial evaluating sifalimumab, an anti-IFN-α monoclonal antibody, shows target neutralisation of a type I IFN signature in blood of dermatomyositis and polymyositis patients
por: Higgs, Brandon W, et al.
Publicado: (2014) -
Clinical Presentation and Evaluation of Dermatomyositis
por: Marvi, Umaima, et al.
Publicado: (2012) -
Distinct purpuric lesions in patients with dermatomyositis
por: Cho, Sung Kyung, et al.
Publicado: (2021)