Small Interfering RNA Targeted to IGF-IR Delays Tumor Growth and Induces Proinflammatory Cytokines in a Mouse Breast Cancer Model

Insulin-like growth factor I (IGF-I) and its type I receptor (IGF-IR) play significant roles in tumorigenesis and in immune response. Here, we wanted to know whether an RNA interference approach targeted to IGF-IR could be used for specific antitumor immunostimulation in a breast cancer model. For t...

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Detalles Bibliográficos
Autores principales: Durfort, Tiphanie, Tkach, Mercedes, Meschaninova, Mariya I., Rivas, Martín A., Elizalde, Patricia V., Venyaminova, Alya G., Schillaci, Roxana, François, Jean-Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250415/
https://www.ncbi.nlm.nih.gov/pubmed/22235273
http://dx.doi.org/10.1371/journal.pone.0029213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250415/
https://www.ncbi.nlm.nih.gov/pubmed/22235273
http://dx.doi.org/10.1371/journal.pone.0029213

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